To analyze the incidence and influencing factors of lower extremity deep vein thrombosis in patients with endometrial cancer after radical surgery

Article ID: 4809

Abstract

To evaluate the incidence of lower extremity deep vein thrombosis (DVT) in patients with endometrial cancer after radical resection, and to investigate the related influencing factors. Methods: A total of 105 patients with endometrial cancer who underwent radical resection in our hospital from November 2022 to November 2023 were selected to observe the occurrence of postoperative DVT, and were divided into DVT group and non-DVT group. Logistic regression model was constructed to analyze the influencing factors of DVT in patients with endometrial cancer after radical resection. Results The incidence of DVT was 17.14% (18/105) 3 days after radical resection of endometrial cancer. The age ≥60 years old, the proportion of diabetes, the proportion of operation time ≥2 hours, and the expression level of D-D in the occurrence group were higher than those in the non-occurrence group, and the differences were statistically significant (P < 0.05). There were no significant differences in long-term smoking, long-term drinking, emaciation, degree of differentiation, hypertension, tumor stage, history of varicose veins, nerve invasion, TT and FIB levels between the two groups (P > 0.05). Logistic multiple regression model showed that age, diabetes, operation time and high level of D-D were the influencing factors of lower extremity deep vein thrombosis in patients with endometrial cancer after radical operation (OR > 1, P < 0.05). Conclusions Patients with endometrial cancer have a higher risk of DVT after radical operation, and there are many influencing factors. Age, diabetes, operation time and high level of D-D are the influencing factors of DVT in patients with endometrial cancer after radical operation.