A comparative study on the effects of music intervention on anxiety, depression, and immune function indicators in cancer patients
Abstract
Background: Based on the bidirectional regulation of modulation of psychological emotion and physiological immune function through the neural auditory pathway, music intervention has shown important value in the integrated treatment of cancer. This study adopted a randomized controlled trial method; 180 cancer patients were randomly assigned to the experimental group (individualized music therapy) and the control group (routine care) respectively, and the subjects were assessed before and after an 8-week intervention. The main outcome was the change in anxiety and depression score (HADS) and immune function (CD4+/CD8+) and IL-6. Methods: The results showed that the intervention group HADS-A score decreased by 40.2%, and the CD4+/CD8 plus ratio increased by 33.3%, and the content of IL-6 decreased by 38.8%. In addition, the emotional improvement was significantly positively correlated with the change in immune function (r = −0.42). Results: The results showed that music intervention can simultaneously improve the psychological state and immune function of cancer patients, which may be realized through the modulation of psychoneuroimmunological.
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